re: Angled knee brace question

I have a lot more carpentry experience than I do woodworking experience, so maybe I can help here. Anything less than 45/45 is going to sacrifice some strength. The question is, can the construction technique survive the difference? What is the intended purpose of the knee braces? What other bracing and supporting structures are there? Can you post a little more info and maybe a pic or drawing of the project? Are you using them to support a cantilever? Shooting from the hip, you’ll probably be fine as long as the braces are well anchored. You could also consider a curved knee brace, depending on length/width of the brace.