For me it's the first tissue out, usually comes with 3 or 4 .
The last one can be more than just frustrating. When a sneeze is coming on, reaching for the straggler usually ends up with a handful of sneeze juice and with the cats out of the house, no self cleaning "rags" handy. 

It's just wrong I tell ya! 


That has to be one of the best boxes I've seen Tony, you lucky snot! 🤠